In Tom Clancy's Rainbow Six: Vegas 2, there is an Achievement/Trophy named 'My Name is Sam' for which the player must get five headshot kills in a row while using a silenced weapon.

In Tom Clancy's Rainbow Six: Vegas, there is a Splinter Cell: Chaos Theory arcade machine in Dante's Casino that has Sam on it.

In Metal Gear SolidВ : Peace Walker, the male POW's facial features bear a resemblance to Fisher.

Big Boss's arrival in the teaser for Metal Gear Solid V: Ground Zeroes (then titled simply as Metal Gear Solid: Ground Zeroes) mirrors that of Fisher's, down to the night vision goggles.

Sam is parodied in one of the Trailers for Metal Gear Solid 4: Guns of the Patriots, at first it appears to be him although it is revealed to be Naked Snake/Big Boss wearing a pair of night vision goggles similar to Sam's trifocal multi-vision goggles.

'Sam' is a reference to Sam Fisher while 'Gabe' refers to Gabe Logan, protagonist of the Syphon Filter series. Monkey' minigame mode of Metal Gear Solid 3: Snake Eater in which the main character of the mini-game Naked Snake/Big Boss is talking to Colonel Campbell about the possibility of getting someone else such as 'Sam' or 'Gabe' to do the work. Naked Snake/Big Boss wear Multi-Vision Goggles in Metal Gear Solid 4 Trailer E3 2005 from Metal Gear Solid 3's 'Secret Theater' when encountering Raiden.

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